Mammadov SA, Ladokhina NP, Shakhgel’dieva LM, Mammadova SI, Aliyeva LI
SYNTHESIS OF CONJUGATED SULFONAMIDES AND THEIR HETEROCYCLIC DERIVATIVES. |
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Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-06-38-1
DOI: http://dx.doi.org/10.15863/TAS.2016.06.38.1
Language: English
Citation: Mammadov SA, Ladokhina NP, Shakhgel’dieva LM, Mammadova SI, Aliyeva LI (2016) SYNTHESIS OF CONJUGATED SULFONAMIDES AND THEIR HETEROCYCLIC DERIVATIVES. ISJ Theoretical & Applied Science, 06 (38): 1-5. Soi: http://s-o-i.org/1.1/TAS-06-38-1 Doi: http://dx.doi.org/10.15863/TAS.2016.06.38.1 |
Pages: 1-5
Published: 30.06.2016
Abstract: Ethoxymethylene malonodinitrile was found to be an active reagent in the synthesis of N-2,2-dicyanoethylene sulfonamides. In the obtained compounds, the nitrile groups had different spatial arrangements, and, therefore, upon their interaction with hydrogen sulfide, even in the cold, only one nitrile group transformed into the thioacetamide group. The interaction between the sulfonamides and hydrazine and hydroxylamine produced pyrazoline- and oxazoline derivatives of sulfonamides. Upon reaction with arylsulfonyl guanidine, ethoxymethylene malonodinitrile easily underwent heterocyclization with a high yield of N-3-amino-4-Z-R-arylsulfonyl pyrimidines.
Key words: hetaryl sulfonamides, ethoxymethylene malonodinitrile, pyrimidine-, oxazoline- and pyrazoline sulfonamides, alkylating agent.
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