Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-09-65-25
DOI: https://dx.doi.org/10.15863/TAS.2018.09.65.25
Language: English
Citation: Gulbaz S, Rehman S, Khalid A (2018) ROLE OF MISOPROSTOL IN PREVENTING COMPLICTIONS AFTER MISCARRIAGE. ISJ Theoretical & Applied Science, 09 (65): 154-159. Soi: http://s-o-i.org/1.1/TAS-09-65-25 Doi: https://dx.doi.org/10.15863/TAS.2018.09.65.25 |
Pages: 154-159
Published: 30.09.2018
Abstract: Objective: This study was conducted to determine role of Misoprostol in preventing post miscarriage complications in first trimester of pregnancy. Design and Setting: This is an observational type of prospective study. This study was carried out in Alkhidmat Mansoorah Hospital Lahore, Pakistan. Duration of study: Study was started in July 2017 and completed in December 2017 comprising on 7 months duration. Patients and Methods: In this study all those cases were included which presented with incomplete or missed miscarriage in first trimester of pregnancy. Dosage of 600 mcg misoprostol was given one time for incomplete miscarriage and repeated doses of 600 mcg were given to the females with 4 hours interval with missed miscarriage via sublingual route. Effect of misoprostol was observed in study group for 10-15 days. Only vitally stable patients were included in this study. Patients with excessive vaginal bleeding after miscarriage, abdominal pain, anemia and vitally unstable due to complications of miscarriage were not included in this study. These cases were underwent evacuation and curettage of retained products of conception. A Performa was designed containing all necessary information regarding age, duration of pregnancy, post miscarriage complications, blood loss, dosage of misoprostol, its side effects and satisfaction of patients towards this treatment. Results: Total 75 cases were studied belonging to different age groups with minimum age of the female 21 years and maximum age of 37 years. Mean age of patients in study group was 34.5 years. Post miscarriage major complication reported was mild blood loss in 13 cases, moderate blood loss in 53 cases and severe bleeding in 12 cases was reported. Single dosage of misoprostol was given in 15 cases, double dosage given in 53 cases and three doses were given in 7 cases. After giving misoprostol its side effect reported were Nausea and vomiting in 4 cases, fever with chills in 8 cases, abdominal pain in 4 cases, diarrhea in 10 cases, flatulence in 9 females and headache was reported in 11 cases. Out of 75 cases 24 cases showed various side effects of this drug while in remaining cases no side effect was seen. In our study group 72 patients successfully responded to this management while 3 cases did not respond and surgery was undertaken in them. So success rate was 96%. Conclusion: Miscarriage is associated with various complications and out of which hemorrhage is a serious complication leading to death. These complications can be reduced by safe method of miscarriage using misoprostol via sublingual route. It is cheap and successful method.
Key words: Misoprostol uses, first trimester miscarriage, side effects of misoprostol, incomplete miscarriage.
|
