Yurchenko, O. I., Chernozhuk, T. V., & Kravchenko, O. A.
Attestation of the test sample of sodium cefazolin for the determination of the accompanying impurities by the method of liquid chromatography in interlaboratory comparative test. |
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Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-08-76-19
DOI: https://dx.doi.org/10.15863/TAS.2019.08.76.19
Language: English
Citation: Yurchenko, O. I., Chernozhuk, T. V., & Kravchenko, O. A. (2019). Attestation of the test sample of sodium cefazolin for the determination of the accompanying impurities by the method of liquid chromatography in interlaboratory comparative test. ISJ Theoretical & Applied Science, 08 (76), 130-137. Soi: http://s-o-i.org/1.1/TAS-08-76-19 Doi: https://dx.doi.org/10.15863/TAS.2019.08.76.19 |
Pages: 130-137
Published: 30.08.2019
Abstract: Certification of a test sample of cefazolin sodium was performed to determine the accompanying impurities in the professional testing program. The adscripted value of the content of the accompanying impurities in the test sample of cefazolin sodium was obtained and the homogeneity of the test sample of cefazolin sodium in the content of the accompanying impurities was confirmed. It is established that the number of accompanying impurities meets the requirements of the State Pharmacopoeia of Ukraine (SPhU). The suitability parameters of the chromatographic system meet the requirements of SPhU. It is established that the test sample is homogeneous. All the questions regarding the professional testing program, the use of liquid chromatography are represented in [1,p.17;2,p.4;3,p.1;4,p.34;5,p.19;6,p.1090;7,p.7;8,p.2;9,p.1;10,p.93;11,p.36;12,p.12;13,p.350;14,p.235;15, p.262;16,p.13; 17,p.7;18,p.343;19,p.35;20,p.16;21,p.65;22,p.59;23,p.55,24,p.137;25,p.36].
Key words: professional testing program, test sample, certification, high effective liquid chromatography, suitability check of the chromatographic system.
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